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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APRT
All Species:
25.76
Human Site:
S161
Identified Species:
70.83
UniProt:
P07741
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07741
NP_000476.1
180
19608
S161
V
S
L
V
E
L
T
S
L
K
G
R
E
K
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089867
180
19643
S161
V
S
L
V
E
L
T
S
L
K
G
R
E
K
L
Dog
Lupus familis
XP_536752
180
19672
S161
V
S
L
V
E
L
T
S
L
K
G
R
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P08030
180
19717
S161
V
S
L
V
E
L
T
S
L
K
G
R
E
R
L
Rat
Rattus norvegicus
P36972
180
19527
S161
V
S
L
V
E
L
T
S
L
K
G
R
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511761
181
19919
T162
V
T
V
I
E
L
T
T
L
R
G
K
E
K
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956962
177
19360
Y159
L
V
V
V
E
L
K
Y
L
N
G
S
D
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397043
178
20028
G159
L
T
I
I
E
L
I
G
L
K
G
R
E
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788872
183
20261
D163
L
V
I
I
E
L
T
D
L
K
G
K
E
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.5
85.5
N.A.
82.2
86.6
N.A.
62.4
N.A.
N.A.
55.5
N.A.
N.A.
48.8
N.A.
48
Protein Similarity:
100
N.A.
98.3
93.8
N.A.
93.3
95
N.A.
80.1
N.A.
N.A.
74.4
N.A.
N.A.
68.3
N.A.
69.9
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
53.3
N.A.
N.A.
46.6
N.A.
N.A.
60
N.A.
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
N.A.
66.6
N.A.
N.A.
86.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
100
0
0
0
0
0
0
0
89
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
100
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
34
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
12
0
0
78
0
23
0
89
0
% K
% Leu:
34
0
56
0
0
100
0
0
100
0
0
0
0
0
89
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
67
0
12
0
% R
% Ser:
0
56
0
0
0
0
0
56
0
0
0
12
0
0
0
% S
% Thr:
0
23
0
0
0
0
78
12
0
0
0
0
0
0
0
% T
% Val:
67
23
23
67
0
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _